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DIVERSITY

CHEMICAL

ENDANGERED

Aster alpinus

Exploring chemical diversity

Leonardo Saldanha

My research is centered on the study of the chemical diversity that might be lost with vanishing plants. I've been working to develop a large-scale metabolomics research workflow using material from herbaria and botanical gardens collections to accelerate chemical knowledge of endangered species of the world's flora.

Selecting material of Palicourea corymbifera, collected in 1977 in the brazilian Amazon, preserved in the Herbarium of the University of Zurich and the Swiss Federal Institute of Technology (ETH) in Zurich.

Conservation of the endangered chemistry

Humanity strongly relies on plant’s chemodiversity for foods, fibres, energy and medicines. However, little is known about how much of the chemical diversity is threatened by plant extinction.Through my research, I aim to generate new information useful to guide conservation plans and studies in regions with a high density unique chemical diversity (hotspots) or of overlooked endangered plants (darkspots). 

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Metabolomics approach

Integrating analytical and computational metabolomic approaches, I address both fundamental and applied questions about phytochemical diversity of natural products. I have combined and optimised cutting-edge techniques such as molecular networking, PCA-based structural positioning, and spectral bases to navigate in chemical spaces and speed up the identification of biologically relevant natural products.

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